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Cellular dermatofibromas are a distinct subtype of dermatofibromas, classified as noncancerous tumors that often manifest as solid nodules, predominantly on the legs. Unlike typical dermatofibromas that remain superficial to the skin, cellular variants extend deeper, reaching the subcutaneous tissue, the skin's lowest layer.

Characteristics and Recurrence

These cellular dermatofibromas have a higher recurrence rate post-treatment compared to other dermatofibromas. In some cases, they may cause necrosis within the tumor, indicating cell or tissue death.

Malignancy and Demographics

It's important to note that cellular dermatofibromas are nonmalignant. However, they have a greater propensity to metastasize compared to other types. They are most commonly found in individuals aged between 20 to 49, with a higher incidence in women.

Prevalence

Dermatofibromas, including the cellular variant, are relatively common, with an occurrence rate of about 3% among all skin lesions.

Causes and Symptoms

The exact cause of cellular dermatofibromas is not well understood. However, it's believed that approximately one in five cases may be linked to an injury or wound at the site of the lesion. These nodules can also arise spontaneously without an identifiable cause.

Individuals with compromised immune systems are more prone to developing multiple dermatofibromas, particularly those with conditions such as HIV/AIDS.

Diagnosis

A healthcare provider can diagnose a cellular dermatofibroma through visual inspection and may perform a skin biopsy to confirm the diagnosis. A biopsy involves the removal of a small tissue sample, which is then examined under a microscope by a pathologist.

Treatment

Since cellular dermatofibromas are noncancerous, they do not always require treatment. However, if the nodule is large or causing discomfort, healthcare providers may opt for removal through a brief in-office procedure. Treatment options include steroid injections to alleviate pain or reduce the size of the lesion, or surgical excision.

Prevention and Prognosis

Currently, there is no known method to prevent cellular dermatofibromas. The prognosis for these nodules is generally good, as they rarely cause significant discomfort or harmful symptoms. However, due to their increased likelihood of recurrence, ongoing monitoring may be necessary.

Living with Cellular Dermatofibromas

Patients may have various questions for their healthcare providers, such as the likely cause of the dermatofibroma, whether the skin growth is a dermatofibroma or another condition, the necessity of treatment, and the benefits and risks associated with removal.

Distinguishing Dermatofibromas from Moles

Differentiating between a cellular dermatofibroma and a mole can be challenging. A dermatofibroma may indent when gently pinched, unlike a mole, which remains elevated above the skin surface.

Cellular dermatofibromas, while more likely to recur and spread compared to other dermatofibromas, are still noncancerous and typically do not require treatment unless they cause discomfort or distress. If removal is necessary, it is usually a brief outpatient procedure. It is essential for individuals with new or changing skin growths to consult with healthcare providers for accurate diagnosis and appropriate management.