Principles and methods of treatment for neonatal phenylketonuria

PKU is a genetic metabolic disorder that can be controlled through diet. pku treatment Natural foods contain a certain amount of low protein phenylalanine, which can cause malnutrition.

It is important to eat foods that are low in phenylalanine for treatment. Let's look at the principles of treatment:

(1) Early treatment: It is best to treat immediately after diagnosis, preferably shortly after birth to prevent the better, so that the development of the child's intelligence can be close to normal.

(2) Prevention of phenylalanine absorption: Phenylalanine is an amino acid required for growth and metabolism in the body.

To prevent brain damage, it is important to reduce the absorption of phenylalanine from food. Under normal circumstances, it is best to maintain blood phenylalanine concentrations in the range of 120-360 μmol/L.

Investigate individual diets: Since not all children have the same tolerance to phenylalanine, dietary adjustments are different in this case. The handling of low-phenylalanine formula should also be kept above at least 12.

(4) Pre-pregnant women: Women who are expecting a child may want to adjust and control their diet prior to pregnancy to prevent adverse phenylalanine reactions.


Are potatoes safe for PKU?

It is acceptable to utilize foods like yoghurt, cow's milk, morning cereals, rice, peas, spinach, broccoli, and potatoes to make up the daily protein allowance for protein tolerance up to 10 g (500 mg) (phenylalanine).

PKU: Is it autoimmune?

Patients with phenylketonuria (PKU), a hereditary metabolic disease, are unable to convert phenylalanine into tyrosine. PKU has been linked to several autoimmune illnesses, although the coexistence of PKU and juvenile idiopathic arthritis (JIA) has not been documented.

Can PKU lower IQ?

If therapy is not initiated soon after birth, phenylketonuria (PKU) is known to have a devastating impact on early intellectual development, leading to an IQ of 30 to 40, significant behavior issues, and severe seizures.

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